Contraindications

(factors that increase the risks involved in carrying out medical procedures or using particular medication)

Summary

Contraindications for apomorphine injections:

• pronounced dyskinesias

• pronounced orthostatic blood pressure reactions

• clinically significant dementia, making it impossible to understand the treatment and its effects

• lack of compliance from patient and support from carers/primary health care professionals

• previous history of apomorphine intolerance.

Contraindications for apomorphine infusions:

• pronounced tendency towards hallucinations and psychotic side effects

• pronounced dementia, making it impossible to understand the treatment and its effects

• lack of compliance from patient and lack of support from carers/primary health care professionals

• previous history of apomorphine intolerance.

Contraindications for levodopa/carbidopa infusions:

• pronounced dementia, making it impossible to understand the treatment and its effects

• contraindications for abdominal surgery

• lack of compliance from patient and lack of support from carers/primary health care professionals.

Contraindications for DBS:

• being of the age of 70 or older

• significant cognitive decline or dementia

• depression or anxiety that cannot be adequately controlled with pharmacological therapy

• contraindications for brain surgery.